Royal Air Force Typhoon FGR4s have conducted a mission with French aircraft in a combined operation on an hidden munitions depot in Syria operated by the Daesh militant organization, per a report from the UK Ministry of Defence.
The facility, located using intelligence, was believed to be housing weapons and explosive materials, the announcement noted, and was positioned in mountains just above the historic site of Palmyra in central Syria.
"Our fighter planes employed laser-guided Paveway IV weapons to strike a number of entry passages leading to the site... preliminary assessments indicate the objective was successfully hit," the ministry announced.
There was no indication of any civilian casualties in the operation on Saturday evening and every plane involved returned safely, the defence officials confirmed.
The Typhoon fighters were assisted by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as Daesh - established extremist governance over large swathes of Iraq and Syria before its territorial defeat in 2019.
"This operation shows the UK's leading role, and determination to stand shoulder to shoulder with our allies, to eliminate any resurgence of the terrorist group and their violent and radical beliefs in the Middle East," Britain's Defence Chief John Healey said.
British military aircraft have carried out overwatch operations over Syrian airspace to "deter any attempted resurgence" of Islamic State following its routing at the Baghuz confrontation in the year 2019, the MoD reported.
"I want to thank every member of our armed forces involved in this operation for their skill and their valour," he said. "They were part of numerous British personnel on duty over the holidays. This operation, to take out terrorist threats who threaten our security, shows how British military are ready to step up, all year round, protecting the UK within its borders and strong abroad."
In December, the US military conducted what it described as a "major assault" on IS targets in Syria, subsequent to an ambush resulted in the deaths of two US troops and a civilian linguist in Palmyra.
The United Nations says Daesh still has between 5,000 and 7,000 militants in both countries.